Bioorganic Chemistry
Kinetic Isotope Effects
The kinetic isotope effect (KIE) is a phenomenon associated with isotopically substituted molecules exhibiting different reaction rates. Isotope effects such as…
July 10, 2021 · Rajil TLLatest articles
Bioorganic Chemistry
Kinetic Versus Thermodynamic Products
Kinetic products form the fastest. They usually occur at or below 0°C. This is also known as the…
July 10, 2021 · Rajil TLBioorganic Chemistry
The Principle of Microscopic Reversibility
The principle of microscopic reversibility applies to any molecular process; it is inferred from the fact that such…
July 10, 2021 · Rajil TL
Bioorganic Chemistry
Definition of a Reaction Intermediate
What exactly is a reaction intermediate? A reaction intermediate is formed from the reactants in a chemical reaction, and reacts…
July 10, 2021 · Rajil TL
Bioorganic Chemistry
Transition state
The transition state of a chemical reaction is a particular configuration along the reaction coordinate. It is defined as the state corresponding to…
July 10, 2021 · Rajil TL
Bioorganic Chemistry
Ester Enolates
we introduced the enolates of aldehydes and ketones (review) and looked at their reactions as C nucleophiles (review). These enolates…
July 10, 2021 · Rajil TL
Bioorganic Chemistry
Acid-Catalyzed Ester Hydrolysis
Water the Destroyer Imagine that water, the stuff you drink everyday, is actually a superhero with a cape,…
July 10, 2021 · Rajil TL
Bioorganic Chemistry
Reaction with Primary Amines to form Imines
The reaction of aldehydes and ketones with ammonia or 1º-amines forms imine derivatives, also known as Schiff bases (compounds having…
July 10, 2021 · Rajil TL
Bioorganic Chemistry
Nomenclature of Aldehydes & Ketones
Aldehydes and ketones contain the carbonyl group. Aldehydes are considered the most important functional group. They are often…
July 10, 2021 · Rajil TL
Bioorganic Chemistry
Acetal Formation
Introduction It has been demonstrated that water adds rapidly to the carbonyl function of aldehydes and ketones to…
July 10, 2021 · Rajil TL