Second Law of Thermodynamics: Entropy
The second law of thermodynamics states that the universe (i.e. all systems)…
Kinetic Isotope Effects
The kinetic isotope effect (KIE) is a phenomenon associated with isotopically substituted molecules exhibiting…
Kinetic Versus Thermodynamic Products
Kinetic products form the fastest. They usually occur at or below 0°C.…
The Principle of Microscopic Reversibility
The principle of microscopic reversibility applies to any molecular process; it is…
Transition state
The transition state of a chemical reaction is a particular configuration along the reaction coordinate. It is…
Acid-Catalyzed Ester Hydrolysis
Water the Destroyer Imagine that water, the stuff you drink everyday, is…
Reaction with Primary Amines to form Imines
The reaction of aldehydes and ketones with ammonia or 1º-amines forms imine derivatives, also…
Acetal Formation
Introduction It has been demonstrated that water adds rapidly to the carbonyl…
Definition of Steric Effect
In general, the steric effect refers from the fact that the atoms composing molecules…




